To prevent fluid volume overload, what medication can be given between transfusions?

• A. Insulin
• B. Antibiotic
• C. Epinephrine
• D. Lasix

Answer: (D)

The main idea is preventing excess fluid in the body between transfusions by promoting urine output. Lasix, a loop diuretic, works by blocking Na+-K+-2Cl- reabsorption in the loop of Henle, which causes the kidneys to excrete more sodium and water. This reduces circulating blood volume and preload, lowering the risk of fluid overload and pulmonary congestion that can occur with transfusions, especially in patients with heart or kidney impairment. Other options don’t help with removing fluid: insulin controls glucose, an antibiotic treats infection, and epinephrine is used for allergic reactions or shocks. When using a diuretic, monitor urine output, electrolytes, and hydration status to avoid dehydration or electrolyte disturbances.