If patient develops flushing, itching, tachycardia during IV infusion, what should you do first?

• A. Stop the IV
• B. Slow the infusion down
• C. Increase the rate
• D. Notify provider

Answer: (B)

When a patient develops flushing, itching, and tachycardia during IV infusion, this signals a possible infusion-related reaction. The priority is to reduce further exposure to the drug while you assess the patient. Slowing the infusion rate accomplishes this by decreasing the amount entering the circulation at once, which can lessen symptoms and prevent progression to a more severe reaction.

While slowing the infusion, monitor vital signs, assess for additional symptoms (shortness of breath, wheezing, hypotension), and ensure the IV line remains patent. If symptoms persist or worsen, follow protocol to stop the infusion and notify the provider. Increasing the rate would likely worsen the reaction, and stopping the IV is reserved for more severe or rapidly progressing cases or as directed by protocol.