If a patient has a fever of 100.4 F before starting a blood transfusion, what is the recommended action?

• A. Ask the provider about whether to proceed
• B. Proceed with transfusion if asymptomatic
• C. Cancel the transfusion
• D. Administer fever-reducing meds and continue

Answer: (A)

Fever before starting a transfusion signals a potential infection or inflammatory process, and it isn’t safe to proceed without clinician input. The right move is to hold the transfusion and contact the provider to determine whether to delay, treat underlying cause, or proceed with precautions. Premedicating with fever reducers and continuing, or starting the transfusion without assessment, can mask signs of a reaction or worsen an underlying infection. The provider may order tests, antibiotics, or a plan to reschedule the transfusion based on the patient’s condition.