During a transfusion reaction with symptoms appearing mid-transfusion, what is the immediate action?

• A. Stop the transfusion, maintain IV line with saline, call the provider, and monitor vital signs.
• B. Continue the transfusion and monitor vitals.
• C. Stop the transfusion and disconnect IV line.
• D. Notify a supervisor after finishing the transfusion.

Answer: (A)

When a transfusion reaction occurs, the first action is to stop the transfusion immediately. This halts further exposure to the donor blood and helps prevent the reaction from worsening. At the same time, keep the IV line with normal saline to maintain venous access for potential rapid fluid administration and medications. Then promptly notify the provider so orders can be given and the transfusion reaction protocol can be activated, while continuously monitoring the patient’s vital signs to gauge stability. Continuing the transfusion would allow the reaction to progress, disconnecting the IV line would remove access for treatment, and delaying notification would delay essential care.